Ranbaxy halts generic Lipitor production after recall: FDA












(Reuters) – Indian generic drugmaker Ranbaxy Laboratories will stop manufacturing its version of Pfizer Inc‘s cholesterol fighter, Lipitor, while it gets to the bottom of the cause of a recent recall, the U.S. Food and Drug Administration said on its website.


Earlier this month, Ranbaxy recalled certain lots of the widely used cholesterol lowering medicine known generically as atorvastatin at doses of 10 milligrams, 20 mg and 40 mg after the company discovered contamination with tiny glass particles.












There have so far been no reports of patients being harmed due to the glass particulates, the FDA said.


The agency said it does not anticipate drug shortages due to the recall as several other companies also produce generic Lipitor, while Pfizer still sells its branded version.


FDA said it was monitoring the situation and working with other manufacturers to ensure adequate supply in order to avoid shortages of atorvastatin as a result of the recall.


During its first six months on the market, when it enjoyed marketing exclusivity, atorvastatin generated sales of nearly $ 600 million for Ranbaxy, according to Bhagwan Singh Chaudhary, a research associate at the brokerage IndiaNivesh


FDA said it will continue to oversee the recall process and work with the Ranbaxy to resolve pharmaceutical quality issues.


The recall is the latest in a series of manufacturing problems at Ranbaxy, which is operating under heightened scrutiny due to past problems that nearly derailed it ability to sell atorvastatin in the United States.


In 2008, the FDA banned the company from importing about 30 drugs after it found manufacturing deficiencies at two of the company’s facilities in India, and Ranbaxy was later accused of falsifying data used in drug applications.


Under a proposed settlement earlier this year, Ranbaxy agreed to engage a third party to conduct a review of its facilities, implement procedures to ensure data integrity in its marketing applications, and ensure it meets good manufacturing practices.


(Reporting by Bill Berkrot)


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The Curious Case of Samsung’s Missing TVs












In August, workers at Samsung Electronics (005930) in the South Korean city of Suwon swathed 60 next-generation televisions in bubble wrap and nailed them into wooden crates. Two weeks later, when the boxes were opened at a Berlin trade show, two TVs were missing. The 55-inch prototypes—each costing $ 10,000 and weighing about 43 pounds—featured breakthrough technology known as organic light-emitting diode displays, which make TVs thinner and help project brighter and sharper images. The suspects: corporate spies.


Thefts of TV sets, diagrams, and circuitry are on the rise, and that’s bad news for Samsung and LG Electronics—the only companies that can commercially produce OLED displays, which the $ 110 billion flat-screen TV industry expects to wow consumers and revive slumping sales. South Korea’s National Industrial Security Center, part of the country’s intelligence agency, last year reported 46 cases involving attempts to steal local companies’ secrets overseas, up from 32 in 2007.












While estimates of industrial espionage are hard to come by, South Korea says foreign theft of its corporate secrets resulted in about $ 82 billion in damages in 2008, the most recent data available, up from $ 26 billion in 2004. The Koreans say 60 percent of victims are small and midsize businesses, and half of all economic espionage originates in China, according to a 2011 U.S. congressional report. “Any company that has a competitive advantage or new technology will be targeted by industrial espionage,” says Frank Schurgers, managing director of security agency Integris International in Berlin.


German companies lose an estimated $ 28 billion to $ 71 billion annually—and as many as 70,000 jobs—due to foreign economic espionage, regulators say. A 2007 survey by the Japanese government found that 35 percent of that country’s businesses reported some form of technology loss. And the FBI says its pending caseload of espionage cases represents losses to the American economy of more than $ 13 billion this fiscal year.


The practice will be tough to stop. In a survey released in June, the Associated Chambers of Commerce and Industry of India found that 35 percent of companies there engaged in some form of corporate espionage to gain advantages over rivals or keep tabs on present and former employees. “Stealing technology basically helps cut down the time to market,” says Jyotirmoy Dutta, a manager at consultant ITC Infotech. “A lot of companies are going to do anything that makes their new product introduction faster.”


As secret-stealing picks up, companies as diverse as Samsung, Apple (AAPL), and Toyota Motor (TM) are boosting security, sometimes at immense cost. Security expert Schurgers says his firm charged a tech company about $ 325,000 to protect one product and that a comprehensive program would easily run into the millions. For businesses that spend heavily on research and development, such security is worth it. Samsung says it spent seven years and “trillions of won” on OLEDs.


Orbotech (ORBK), an Israeli maker of equipment used to test screens for TVs, smartphones, and tablets, says its Korean subsidiary and six local employees have been indicted on suspicion they stole display technology from Samsung. LG says Orbotech workers are suspected of illegally gaining access to its confidential OLED data, too. A probe by Korean police into actions by Orbotech staffers is ongoing, and the company says its Korean subsidiary is cooperating with authorities there.


While it would be difficult to reverse-engineer the fundamentals of OLED technology from the missing televisions, simply understanding how Samsung packed the parts inside the superthin sets would be valuable information for thieves, says Kim Hyung Sik, an analyst at Taurus Investment & Securities in Seoul. “They will be able to get their hands on how components are aligned to make the TVs slimmer,” Kim says. “It saves competitors a lot of time.”


Korean authorities are operating on the assumption that Samsung’s missing TVs were stolen, not lost, says Lee Seung Yong, a senior inspector at Gyeonggi Provincial Police Agency in Suwon, where the company is headquartered. A freight forwarder packed the TVs in wooden boxes that were nailed on five sides and then sealed with a nut and bolt on the sixth. When the boxes arrived at the airport, they weighed the same as at the forwarder’s warehouse, and security cameras en route yielded no clues, according to a police report.


The 14 people involved in transporting the boxes from Samsung to a Korean Air plane were questioned, the report said. Police say they found fingerprints from 14 individuals on the box that the missing TVs were packed in. Although they didn’t say whether the prints matched those of the people who were questioned, police have concluded the theft likely didn’t occur in Korea. They’re now coordinating with German authorities.


Since the TVs went missing, Samsung says it’s tightened controls on shipments of equipment to trade shows. The company says it already uses special paper that trips an alarm when someone tries to sneak documents out of its offices. Other companies are also becoming more vigilant. Businesses testing Apple’s iPad before its 2010 release had to promise to secure the tablet in a room with blacked-out windows and key-card locks and keep it tethered to a stationary object, according to persons at the time who were not authorized to speak before plans for the device were released. And visitors to many Toyota facilities are required to seal USB ports on laptops and place blue stickers over mobile-phone cameras.


Even affiliates of LG and Samsung have accused each other of purloining secrets. In July, Samsung asked its rival to apologize after Korean prosecutors investigated employees of LG Display, the company’s panel-making unit, about the theft—so far unsolved—of information on Samsung’s OLED program. LG Display refused to apologize and two months later sued Samsung for allegedly infringing its own OLED patents. A Samsung unit in November asked a Korean intellectual property tribunal to invalidate seven OLED patents held by LG. “The more advanced a technology is, the more attractive it is for companies or countries that don’t have it,” says Shin Hyun Goo, head of external relations at the Korean Association for Industrial Technology Security in Seoul. Samsung and LG “are like mice being eyed by eagles hovering around them.”


9a6f8  comp samsung49 405inline1 The Curious Case of Samsungs Missing TVs


The bottom line: As thefts of secrets in the $ 110 billion TV industry increase, Samsung and other tech companies are beefing up security.


Businessweek.com — Top News


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Rapper PSY wants Tom Cruise to go ‘Gangnam Style’












BANGKOK (AP) — The South Korean rapper behind YouTube’s most-viewed video ever has set what might be a “Mission: Impossible” for himself.


Asked which celebrity he would like to see go “Gangnam Style,” the singer PSY told The Associated Press: “Tom Cruise!”












Surrounded by screaming fans, he then chuckled at the idea of the American movie star doing his now famous horse-riding dance.


PSY’s comments Wednesday in Bangkok were his first public remarks since his viral smash video — with 838 million views — surpassed Justin Bieber‘s “Baby,” which until Saturday held the record with 803 million views.


“It’s amazing,” PSY told a news conference, saying he never set out to become an international star. “I made this video just for Korea, actually. And when I released this song — wow.”


The video has spawned hundreds of parodies and tribute videos and earned him a spotlight alongside a variety of superstars.


Earlier this month, Madonna invited PSY onstage and they danced to his song at one of her New York City concerts. MC Hammer introduced the Korean star at the American Music Awards as, “My Homeboy PSY!”


Even President Barack Obama is talking about him. Asked on Election Day if he could do the dance, Obama replied: “I think I can do that move,” but then concluded he might “do it privately for Michelle,” the first lady.


PSY was in Thailand to give a free concert Wednesday night organized as a tribute to the country’s revered King Bhumibol Adulyadej, who turns 85 next month. He paid respects to the king at a Bangkok shopping mall, signing his name in an autograph book placed beside a giant poster of the king. He then gave an outdoor press conference, as screaming fans nearby performed the pop star’s dance.


Determined not to be a one-hit wonder, PSY said he plans to release a worldwide album in March with dance moves that he thinks his international fans will like.


“I think I have plenty of dance moves left,” he said, in his trademark sunglasses and dark suit. “But I’m really concerned about the (next) music video.”


“How can I beat ‘Gangnam Style’?” he asked, smiling. “How can I beat 850 million views?”


___


Associated Press writer Thanyarat Doksone contributed to this report.


Asia News Headlines – Yahoo! News


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Samsung takes aim at Japanese rivals with Android camera












SEOUL (Reuters) – South Korean consumer electronics giant Samsung Electronics Co is taking aim at its Japanese rivals with an Android-powered digital camera that allows users to swiftly and wirelessly upload pictures to social networking sites.


The Galaxy camera lets users connect to a mobile network or Wi-Fi to share photographs and video without having to hook up the camera to a computer.












While it’s not the first to the market, Samsung‘s financial and marketing clout suggest it could be the biggest threat to Japanese domination of a digital camera industry which research firm Lucintel sees growing to $ 46 billion by 2017 and where big brands include Canon Inc, Sony Corp, Panasonic Corp, Nikon Corp and Olympus Corp.


“Samsung has a tough row to hoe against the likes of Canon and Nikon in the camera brand equity landscape,” said Liz Cutting, senior imaging analyst at research firm NPD Group. “Yet as a brand known more in the connected electronic device arena, Samsung has a unique opportunity to transfer strength from adjacent categories into the dedicated camera world.”


The Korean group, battling for mobile gadget supremacy against Apple Inc, is already a global market leader in televisions, smartphones and memory chips.


Samsung last year brought its camera and digital imaging business – one of its smallest – under the supervision of JK Shin, who heads a mobile business that generated 70 percent of Samsung’s $ 7.4 billion third-quarter profit.


“Our camera business is quickly evolving … and I think it will be able to set a new landmark for Samsung,” Shin said on Thursday at a launch event in Seoul. “The product will open a new chapter in communications – visual communications,” he said, noting good reviews for the Samsung Galaxy camera which went on sale in Europe and the United States earlier this month.


AIMING AT ‘PRO-SUMERS’


The Galaxy camera, which sells in the United States for $ 499.99 through AT&T with various monthly data plans, features a 4.8-inch LCD touchscreen and a 21x optical zoom lens. Users can send photos instantly to other mobile devices via a 4G network, access the Internet, email and social network sites, edit photos and play games.


The easy-to-use camera, and the quality of the pictures, is aimed at mid-market ‘pro-sumers’ – not quite professional photographers but those who don’t mind paying a premium for user options not yet available on a smartphone – such as an optical, rather than digital, zoom, better flash, and image stabilization.


The appeal of high picture quality cameras with wireless connection has grown as social media services such as Facebook Inc drive a boom in rapid shoot-and-share photos.


“At a price point higher than some entry-level interchangeable-lens cameras, the Galaxy camera should appeal to a consumer willing to pay an initial and ongoing premium for 24/7 creative interactivity,” said Cutting.


Traditional digital camera makers are responding.


Canon, considered a leader in profitability in corporate Japan with its aggressive cost cutting, saw its compact camera sales eroded in the most recent quarter by smartphones, and has just introduced its first mirrorless camera to tap into a growing market for small, interchangeable-lens cameras that rival Nikon entered last year.


Nikon has also recently introduced an Android-embedded Wi-Fi only camera.


($ 1 = 1086.4000 Korean won)


(This story fixes typing error in paragraph 9)


(Additional reporting by Dhanya Skariachan in NEW YORK; Editing by Ian Geoghegan)


Wireless News Headlines – Yahoo! News


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Cate Blanchett in negotiations for evil stepmother in Disney’s Cinderella film












LOS ANGELES (TheWrap.com) – Cate Blanchett is in negotiations to play the evil stepmother in Disney‘s re-imagining of the classic fairytale Cinderella, the “Untitled Cinderella Story,” an individual with knowledge of the situation told TheWrap.


Blanchett would be the first to be cast in the live-action film. It is being directed by Mark Romanek for the studio based on a script by Chris Weitz.












The film is being produced by Simon Kinberg, who is best-known for the “X-Men” series.


The feature was first set up at Disney in May 2010 based on a pitch by Aline Brosh McKenna (“Devil Wear Prada.”), who wrote the initial draft.


Disney set the project up in the wake of its success with “Alice in Wonderland,” an adaptation of the Lewis C. Carroll book that starred Johnny Depp.


Disney representatives could not be reached for comment.


Blanchett can next be seen on screen in “The Hobbit: An Unexpected Journey” on December 14. She was recently confirmed for George Clooney’s upcoming film “The Monuments Men.” She will also be seen in “The Hobbit: The Desolation of Smaug” and “The Hobbit: There and Back Again.”


Cinderella has been adapted for the big screen dozens of times. In Andy Tennant’s 1998 version “Ever After: A Cinderella Story,” Angelica Houston played the evil stepmother. In the TV movie “Cinderella” in 1997, the role was played by Bernadette Peters. Sigourney Weaver voiced the character in “Happily N’Ever After” in 2006. Disney‘s 1950 version featured Eleanor Audley in the voice role of Lady Tremaine, the wicked stepmother.


Movies News Headlines – Yahoo! News


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Arizona declines to set up state-based health insurance exchange












PHOENIX (Reuters) – Arizona Governor Jan Brewer said on Wednesday she was rejecting a major provision of President Barack Obama‘s healthcare reform law that calls for creating state-based health insurance markets where consumers can purchase private, federally subsidized coverage.


Citing lingering questions about the plan and operating costs she said would be passed on to families and small businesses, Brewer, a Republican, said Arizona would join at least 16 other states in opting instead for a federally run health insurance exchange.












Such networks are designed to function as online insurance markets where the uninsured can shop for private health plans offered at federally subsidized rates, and are an integral provision of the Affordable Care Act, a centerpiece of Obama’s first term in office.


Brewer, along with many other Republicans, has been an outspoken critic of Obama’s healthcare overhaul initiative, calling it an “overreaching and unaffordable assault on states’ rights and individual liberty.”


Under a newly extended deadline, states have until December 14 to notify the U.S. Health and Human Services Department whether they intend to comply with the insurance exchange mandate or leave it to the federal government to set up and operate exchanges for them.


Seventeen states plus the District of Columbia have told the Obama administration they intend to move ahead with their own exchanges, while Arizona became the latest of 17 states to reject the plan outright in favor of a federally based exchange, according to the Kaiser Family Foundation, which has closely tracked the issue.


Most of those opting out are states in the Midwest or South. Six more states have sought to join with HHS in setting up a hybrid federal-state network, and 10 states remain undecided, the foundation said.


CALLS OPPOSITION ‘UNWAVERING’


“My opposition to the Affordable Care Act is unwavering, as is my belief that it should be repealed and replaced,” Brewer said in a statement announcing her decision. Republican Mitt Romney, who lost to Obama in the November 6 presidential election, had vowed to repeal the law if elected.


Acknowledging that the law had been upheld as constitutional by the U.S. Supreme Court, and despite her advocacy of greater local control, Brewer said her state would be better off ceding management of a system she said would be dominated by the federal government in any case.


“I have come to the conclusion that the state of Arizona would wield little actual authority over its ‘state’ exchange,” she said.


Although startup costs of exchanges are to be borne by the federal government, Brewer said Arizona stood to incur $ 27 million to $ 40 million in operating expenses starting in 2015, and that those costs would be passed along in the form of higher premiums to policy holders.


Brewer, who has clashed sharply with the Obama administration on a number of issues, especially immigration policy, made her intentions known in a one-page letter to HHS on Wednesday.


The state, which also has a Republican-controlled Legislature, had spent millions of dollars in federal grant money over the past several months laying the groundwork for the possible creation of a healthcare exchange.


Brewer faced heavy lobbying from some conservative Republicans who opposed setting up a state-run exchange, while a number of business groups and healthcare organizations favored creating one. State Democrats also strongly support a state-run exchange.


One top Democratic lawmaker criticized Brewer for “an irresponsible decision” that wasted millions of dollars already spent preparing for a state-run exchange.


“The governor is going to throw that all away so she can push an extremist agenda,” state House of Representatives Minority Leader Chad Campbell said. “We’ve come to expect political grandstanding from her, but this is a whole new level.”


Campbell said in a statement the state exchange that Brewer rejected would be a plus for consumers, giving them more of a say over their healthcare decisions.


“The governor just signed over a lot of power to the federal government,” he added.


(Reporting by David Schwartz; Writing by Steve Gorman; Editing by Cynthia Johnston and Peter Cooney)


Health News Headlines – Yahoo! News


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Report: Economy boosted entrepreneurship in 2011












NEW YORK (AP) — The slow improvement in the economy gave a huge boost to entrepreneurship in the U.S. last year, according to a study released Thursday.


More than 29 million people were starting or running new businesses in 2011, the study by Babson College in Wellesley, Mass., and Baruch College in New York shows. That was a 60 percent gain from 2010, when entrepreneurship was hurt by uncertainty about the economy.












The gain also matched the increase in entrepreneurship recorded in 2005, when the economy and small businesses were booming.


A pickup in entrepreneurship indicates that people were getting more confident about the economy and were therefore willing to take a chance on starting a business. However, it also reflects a still-weak job market: Many people chose to start companies because they couldn’t find jobs or were tired of looking.


Still, researchers at the colleges say the report’s findings are a positive sign for the economy. They found that nearly 40 percent of the entrepreneurs they counted expected to create more than five new jobs each in the next five years. Many economists have said the economy can’t gain momentum unless small businesses pick up the pace of their hiring.


The economy has been showing signs of a slow but steady recovery, led by an improving housing market and greater consumer confidence. Next week will bring several new reports, including the government’s look at the job market in November.


Economy News Headlines – Yahoo! News


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Rugby-England add flyhalf Burns to squad for All Blacks’ test












LONDON, Nov 27 (Reuters) – England called up uncapped Gloucester flyhalf Freddie Burns on Tuesday to their squad for Saturday’s test against New Zealand in place of the injured Toby Flood.


Flood sustained ligament damage to a big toe during the 16-15 loss to South Africa at Twickenham last Saturday.












Owen Farrell, whose last start was in the first test in South Africa this year, is set to replace Flood in the starting XV against the world champions.


Lock Courtney Lawes, who missed England’s first three tests of the November series because of a knee injury, has also been included in the 23-man squad. Two other locks, Mouritz Botha and Tom Palmer, have been omitted.


After beating Fiji in their opening match, England have lost to Australia and the Springboks and now face a daunting match against the All Blacks who are unbeaten in 20 tests since the start of their victorious World Cup campaign last year.


“For those in Saturday’s squad the message is clear – last week we went toe to toe with the second best team in the world and felt we should have won,” England head coach Stuart Lancaster said in a statement.


“Now we have a chance to take on the number one side in front of a passionate Twickenham crowd, who have been fantastic throughout the Internationals, and it is a challenge we will meet head on.” (Reporting by John Mehaffey; Editing by Ken Ferris)


Australia / Antarctica News Headlines – Yahoo! News


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Robbie Williams aims to seal solo legacy with tour












LONDON (Reuters) – Still famous as the in-again/out-again member of chart-topping boyband Take That, British singer Robbie Williams says it is time to get serious as a solo artist and prove his place at the top of the pop pile.


Williams told reporters on Monday he planned a 15-date European stadium tour kicking off in Manchester on June 19, 2013 and concluding in Tallinn, Estonia on August 20.












“I’m buzzing. I’m ready to go. I haven’t done a tour of this size since 2006,” he said in London.


“I think it’s legacy time, because I’m venturing into getting my handicap down at golf and all that business.


“I’m nearly 40, that’s what I’m trying to say. I want to go and seal my place in pop history and go off and deliver a tour of great magnitude while I still can.”


The 38-year-old in fact enjoyed major success after leaving Take That in 1995, producing a string of hit albums and singles including “Angels” and “Millennium” and signing a contract with EMI in 2002 reportedly worth tens of millions.


But by the time his 2006 album “Rudebox” came out followed by “Reality Killed the Video Star” in 2009, he was seen as a dwindling force in British pop who had failed to break the key U.S. market.


Williams rejoined Take That in 2010 and they recorded the hit album “Progress” before touring together in 2011, and the singer said the experience had helped give him confidence to tour large venues again as a solo artist.


“I just ran out of ideas and ran out of a bit of creativity and ran out of energy and did the textbook ‘burnt out’,” he said of the late 2000s.


“But I’ve been working really hard and I needed to do something else, and fortunately it came in the shape of my old band. A lot of demons were vanquished from the past. A lot of wrongs were put to rights.


“That tour last summer was just absolutely incredible. It kick-started my professional career.”


Earlier this month, Williams returned to the top of the album charts with “Take the Crown”.


Asked whether he would consider rejoining Take That again, he replied: “I haven’t officially left … What I do know is that … if we all remain healthy then I will definitely be a part of Take That at some point. It’s joyful being around them.”


Williams conceded it may be too early to talk about his legacy at 38, but added he wanted to “put my stamp down.


“The fact that 40 is looming plays on my mind more than it does on anybody else’s mind. Pop stars cease to be pop stars at 40 and start being old people singing, don’t they?


“There is a forum for a male solo star to get up there in stadiums and own the place and I want that to be me, so I’ve kind of been lethargic for the last couple of albums.”


Williams recently became a father, and said his daughter would accompany him on tour. Olly Murs, who rose to fame on “The X Factor” reality TV show, will support Williams on his tour.


(Reporting by Mike Collett-White, editing by Paul Casciato)


Music News Headlines – Yahoo! News


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Flu Symptoms Drove Boston Mayor to Hospital












When Boston Mayor Thomas Menino ended his vacation in Italy short this fall and checked into a Boston hospital complaining of a respiratory infection, it led doctors to find and treat a blood clot in his leg, a fracture in his back, an infection around the fracture and type 2 diabetes.


Cold and flu symptoms from respiratory infections can be a hassle, but sometimes that fever and cough can be good for just getting people to the doctor.












“That’s why every patient needs a careful evaluation because every once in a while, what the patient thinks is the flu or reports as the flu is not,” said Dr. William Schaffner, chairman of preventative medicine at Vanderbilt University in Tennessee. “I would say 99 percent of people who present to the emergency room and doctor’s office with symptoms of influenza – that is cough, fever and the like – are certainly going to have influenza.”


Click here to read about cold- and flu-fighters.


Menino, 69, arrived at Brigham and Women’s Hospital on Oct. 25, complaining of fatigue and a cough, and doctors described him as “extremely washed out” with some “malaise.” In addition to the respiratory infection, doctors found a blood clot that traveled from Menino’s leg to his lungs.


Respiratory illnesses, like the one that initially drove Menino to seek medical attention, can often range from mild to severe, Schaffner said.


“He was feeling poorly enough to end what was supposed to be a very pleasant vacation, and when he got here, he was very weak and very washed out,” Dr. Dale Adler, Menino’s doctor, said during a press conference in mid-November.


Doctors can usually tell whether flu-like symptoms are the result of a respiratory infection or something else soon after the patient is admitted. If not, they can perform a series of tests to find out.


Click here to read about flu fact and fiction.


(The flu can lead to other ailments, the most common of which is pneumonia, or an infection of the lungs, Schaffner said.


About 1.1 million pneumonia patients were hospitalized and discharged in 2009, according to the latest data from the Centers for Disease Control and Prevention. On average, they stayed in the hospital 5.2 days.)


Weeks later, Menino was still in the hospital. Although his illness and clot had been resolved, he was complaining of back pain, which doctors discovered was the result of a compression fracture and an infection around the fracture.


Finally, doctors discovered that Menino had underlying type 2 diabetes, which may have contributed to the infection, Menino’s doctor said during a press conference on Monday.


It’s not clear how Menino’s initial flu-like symptoms tied into his other ailments, but doctors said they are positive about his prognosis. The mayor relocated to a rehabilitation center on Monday.


“It is a run of bad luck,” Morris said of Menino. “He will rebound from this.”


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