Vanda’s drug for rare disorder meets main trial goal






(Reuters) – Vanda Pharmaceuticals Inc said a late-stage trial of its drug to treat a rare disorder affecting blind people met the main goal of showing improvement over a placebo, sending its shares up as much as 37 percent.


The drug tasimelteon is being tested for non-24-hour disorder, a rare and chronic circadian rhythm disorder for which there is no approved treatment, Vanda said in a statement.






The disorder, in which a person’s body clock does not automatically set to the 24-hour day thereby affecting sleep cycles, affects a majority of blind people.


The main goal of the trial was to reset the rhythm of the hormone melatonin, which controls sleep and wake cycles, to a 24 hour day-night cycle.


The goal also included measuring patients’ clinical response to the drug compared with a placebo.


The study, which enrolled 84 patients, was the first of four studies that form Vanda’s late-stage program for the drug. The drug was well tolerated in the study.


Vanda said it expects results from the second study in the first quarter of 2013, and plans to submit a marketing approval application to the U.S. health regulator in mid 2013.


Shares of the company were up 28 percent at $ 4.12 in heavy volume trade on Tuesday morning on the Nasdaq. Around 2.2 million shares had changed hands by 1007 ET – more than eight times the stock’s average moving volumes.


Tasimelteon received orphan drug status from the U.S. Food and Drug Administration in 2010 and from the European Commission in 2011.


The FDA grants orphan drug status to drugs or biologics that treat a condition affecting less than 200,000 Americans, giving the drugmaker marketing exclusivity for seven years in the United States.


In Europe, the status is granted to drugs treating a condition affecting no more than 5 in 10,000 people in the European Union, and carries a 10-year marketing exclusivity.


Tasimelteon is also being developed as a treatment for Major Depressive Disorder.


Vanda’s schizophrenia drug Fanapt, which is marketed and sold in the United States by Novartis AG, received a negative opinion earlier this month from the European Medicines Agency.


(Reporting by Esha Dey and Vrinda Manocha in Bangalore; Editing by Roshni Menon)


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Instagram Has a Flickr Moment






Once Instagram courted professional photographers. On Dec. 17, it kicked them in the teeth—or so the reaction to the photo-sharing site’s new terms of service suggests. On Instagram, professional photographers were not pleased.


Danny Ghitis: Looks like @instagram is jumping on the copyright infringement boat. Being on the internet doesn’t mean pictures are free, assholes.
Noah Rabinowitz: I’m out.
Jody Rogac: Dear Instagram, you know I love you but this may just be a dealbreaker.






And some reactions on Twitter:
@Amy_Stein: New Instagram TOS take effect Jan 16. Be afraid if you like to get paid for your work.
@MarcDSchiller: Bye, bye @instagram. It was fun while it lasted.
@ChrisSandersNY: What!!!!! Instagram Can Now Sell Users’ Photos Without Paying Or Notifying Them


By the end of the day on Dec. 18, the company had gone into damage-control mode. Instagram co-founder Kevin Systrom wrote in a blog post that the company had “heard loud and clear that many users are confused and upset about what the changes mean.” Many professional photographers interpreted the new Instagram rules as granting the site the right to use and sell photos without notifying or compensating the photographer—something the company does not intend to do, Systrom wrote. “We’re going to modify specific parts of the terms to make it more clear what will happen with your photos,” he wrote. “Please stay tuned.”


It’s not clear whether the pros can be wooed back. Perhaps more than any of Instagram’s users, professional photographers are feeling particularly spurned. In its early days, when Instagram was turning itself from a Foursquare also-ran into a photo-sharing site, it relied on partnerships with professional photographers to promote its service.


Great photographers were featured, giving Instagram cachet and credibility. The New Yorker set up an Instagram feed, then turned it over to a different photographer each week to showcase their work and daily life. National Geographic shared the names and accounts of its photographers for all to follow.


It also provided a community for photographers to see each other’s work and comment directly—a rare thing in the photo world. Photo editors and photo buyers got a view into photographers’ processes and lives. We saw photographers Jake Stangel travel the world and Kendrick Brinson and David Walter Banks fall in love.8e5da  1218 instagram inline405 Instagram Has a Flickr MomentPhotograph by Kendrick BrinsonAtlanta photographer Kendrick Brinson and her husband, David Walter Banks, on Instagram For photographers, it is easier to communicate with images than it is with text, and it is more interesting and rewarding to do so with a community of other photographers and photo lovers than everyone you went to high school with. Lots of people loved Instagram, but as a service, it really did feel tailored for the pros.


The world of professional photo rights is complex, but here is a quick overview: Photo buyers from ad agencies, publishers, newspapers, and magazines pay for use and rights. The amount depends on visibility, circulation, size of use, and a variety of other qualifiers. A magazine like Rolling Stone will pay less to use an image than, for example, Bank of America (BAC) probably would. In most cases, the photographer retains the permanent rights to images unless a fairly high fee is paid or the photographer is working on contract.


Some have suggested that Facebook (FB) is trying to turn Instagram into a stock photography site, à la iStock, or other services that sell images to users. More likely, it’s looking for cover, in case it decides to use images from the site in its own advertising and promotions, or in conjunction with other companies—an issue Systrom alluded to in his post. This same issue comes up every time Facebook changes its user privacy settings. People threaten to leave and don’t, and Facebook doesn’t sell our vacation photos. (At least, it hasn’t yet.)


Here’s the difference: There isn’t a good alternative to Facebook right now. There is a good alternative to Instagram. It’s called Flickr. Even before the Instagram announcement, Yahoo’s (YHOO) Flickr service was starting to show signs of life for the first time in years, with an elegant new app and a renewed commitment to its users. It’s worth remembering where Flickr went wrong in the first place: It thought it was a database of photos, not a community of photographers. That was a mistake—its users knew it, and defected en masse.


Now, anecdotally, they would appear to be coming back. Flickr has a fairly elegant solution for this: It allows photographers to upload their photos under the Creative Commons license or, on the other end of the spectrum, not to be reproduced in any way (these images can’t even be dragged and dropped). That seems fair to me. This morning, I decided to give Flickr another try. It took me only a dozen attempts to remember my password.


Businessweek.com — Top News





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N. Korea displays Kim Jong Il a year after death






PYONGYANG, North Korea (AP) — North Korea unveiled the embalmed body of Kim Jong Il, still in his trademark khaki jumpsuit, on the anniversary of his death Monday as mourning mixed with pride over a recent satellite launch that was a long-held goal of the late authoritarian leader.


Kim lies in state a few floors below his father, national founder Kim Il Sung, in the Kumsusan mausoleum, the cavernous former presidential palace. Kim Jong Il is presented lying beneath a red blanket, a spotlight shining on his face in a room suffused in red.






Wails echoed through the chilly hall as a group of North Korean women sobbed into the sashes of their traditional Korean dresses as they bowed before his body. The hall bearing the glass coffin was opened to select visitors — including The Associated Press — for the first time since his death.


North Korea also unveiled Kim’s yacht and his armored train carriage, where he is said to have died. Among the personal belongings featured in the mausoleum are the parka, sunglasses and pointy platform shoes he famously wore in the last decades of his life. A MacBook Pro lay open on his desk.


North Koreans paid homage to Kim and basked in the success of last week’s launch of a long-range rocket that sent a satellite named after him to space.


The launch, condemned in many other capitals as a violation of bans against developing its missile technology, was portrayed not only as a gift to Kim Jong Il but also as proof that his young son, Kim Jong Un, has the strength and vision to lead the country.


The elder Kim died last Dec. 17 from a heart attack while traveling on his train. His death was followed by scenes of North Koreans dramatically wailing in the streets of Pyongyang, and of the 20-something son leading ranks of uniformed and gray-haired officials through funeral and mourning rites.


The mood in the capital was decidedly more upbeat a year later, with some of the euphoria carrying over from last Wednesday’s launch. The satellite bears one of Kim Jong Il’s nicknames, Kwangmyongsong, or “Lode Star,” a moniker given to him at birth according to the official lore.


Cameras were not allowed inside the mausoleum, and state media did not release any images of Kim Jong Il’s body.


With the death anniversary came a hint that Kim Jong Un himself might soon be a father.


His wife, Ri Sol Ju, was seen on state TV with what appeared to be a baby bump as she walked slowly next to her husband at the mausoleum, where they bowed to statues of Kim’s father and grandfather.


There is no official word from Pyongyang about a pregnancy. In addition, Ri is shown wearing a billowing traditional Korean dress in black that makes it difficult to know for sure.


North Koreans are reluctant to discuss details of the Kim family that have not been released by the state. Still there are rumors even in Pyongyang about whether the country’s first couple is expecting.


To honor Kim’s father, North Koreans stopped in their tracks at midday and bowed their heads as the national flag fluttered at half-staff along streets and from buildings.


Pyongyang construction workers took off their yellow hard hats and bowed at the waist as sirens wailed across the city for three minutes.


Tens of thousands of North Koreans gathered in the frigid plaza outside, newly transformed into a public park with lawns and pergolas. Geese flew past snow-tinged firs and swans dallied in the partly frozen moat that rings the vast complex in Pyongyang’s outskirts.


“Just when we were thinking how best to uphold our general, he passed away,” Kim Jong Ran said at the plaza. “But we upheld leader Kim Jong Un. … We regained our strength and we are filled with determination to work harder for our country.”


Speaking outside the mausoleum, renamed the Kumsusan Palace of the Sun, the military’s top political officer, Choe Ryong Hae, said North Korea should be proud of the satellite, calling it “a political event with great significance in the history of Korea and humanity.”


Much of the rest of the world, however, was swift in condemning the launch, which was seen by the United States and other nations as a thinly disguised cover for testing missile technology that could someday be used for a nuclear warhead.


The test, which the U.N. Security Council said violated a ban on launches using ballistic missile technology, underlined Kim Jong Un’s determination to continue carrying out his father’s hardline policies even if they draw international condemnation.


Washington said Monday it has no option but to seek to isolate Pyongyang further.


“What’s left to us is to continue to increase pressure on the North Korean regime and we are looking at how to best to do that, both bilaterally and with our partners going forward until they (North Korea) get the message. We are going to further isolate this regime,” U.S. State Department spokeswoman Victoria Nuland said.


Some outside experts worry that Pyongyang’s next move will be to press ahead with a nuclear test in the coming weeks, a step toward building a warhead small enough to be carried by a long-range missile.


Despite inviting further isolation for his impoverished nation and the threat of stiffer sanctions, Kim Jong Un won national prestige and clout by going ahead with the rocket launch.


At a memorial service on Sunday, North Korea’s top leadership not only eulogized Kim Jong Il, but also praised his son. Kim Yong Nam, president of the Presidium of North Korea’s parliament, called the launch a “shining victory” and an emblem of the promise that lies ahead with Kim Jong Un in power.


The rocket’s success also fits neatly into the narrative of Kim Jong Il’s death. Even before he died, the father had laid the groundwork for his son to inherit a government focused on science, technology and improving the economy. And his pursuit of nuclear weapons and the policy of putting the military ahead of all other national concerns have also carried into Kim Jong Un’s reign.


In a sign of the rocket launch’s importance, Kim Jong Un invited the scientists in charge of it to attend the mourning rites in Pyongyang, according to state media.


The reopening of the mausoleum on the anniversary of the leader’s death follows tradition. Kumsusan, the palace where his father, Kim Il Sung, served as president, was reopened as a mausoleum on the anniversary of his death in 1994.


___


Associated Press writers Hyung-jin Kim in Seoul, South Korea, and Matthew Pennington in Washington contributed to this report. Follow Jean Lee, AP’s bureau chief for Pyongyang and Seoul, at www.twitter.com/newsjean.


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Judge rejects Apple injunction bid vs. Samsung






(Reuters) – A U.S. judge on Monday denied Apple Inc‘s request for a permanent injunction against Samsung Electronics‘ smartphones, depriving the iPhone maker of key leverage in the mobile patent wars.


Apple had been awarded $ 1.05 billion in damages in August after a U.S. jury found Samsung had copied critical features of the iPhone and iPad. The Samsung products run on the Android operating system, developed by Google.






Apple and Samsung are going toe-to-toe in a patents dispute that mirrors the struggle for industry supremacy between the two companies, which control more than half of worldwide smartphone sales.


For most of the year, Apple had been successful in its U.S. litigation campaign against Samsung. Apple convinced U.S. District Judge Lucy Koh in San Jose, California to impose two pretrial sales bans against Samsung — one against the Galaxy Tab 10.1, and the other against the Galaxy Nexus phone.


Apple then sought to keep up the pressure after its sweeping jury win. It asked Koh to impose a permanent sales ban against 26 mostly older Samsung phones, though any injunction could potentially have been extended to Samsung’s newer Galaxy products.


Yet the jury exonerated Samsung on the patent used to ban Galaxy Tab 10.1 sales, and Koh rescinded that injunction. Then, in October, a federal appeals court reversed Koh’s ban against the Nexus phone.


In her order late on Monday, Koh cited that appellate ruling as binding legal precedent, ruling that Apple had not presented enough evidence that its patented features drove consumer demand for the entire iPhone.


“The phones at issue in this case contain a broad range of features, only a small fraction of which are covered by Apple’s patents,” Koh wrote.


“Though Apple does have some interest in retaining certain features as exclusive to Apple,” she continued, “it does not follow that entire products must be forever banned from the market because they incorporate, among their myriad features, a few narrow protected functions.”


An Apple spokeswoman declined to comment on Koh’s ruling, and a Samsung representative could not immediately be reached.


In a separate order on Monday, Koh rejected a bid by Samsung for a new trial based on an allegation that the jury foreman was improperly biased in favor of Apple.


The case in U.S. District Court, Northern District of California is Apple Inc. vs. Samsung Electronics Co Ltd et al, 11-1846.


(Reporting by Dan Levine in Oakland, California; Editing by Ron Popeski)


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Participant Media plans cable TV network targeting millenials






LOS ANGELES (Reuters) – Entertainment company Participant Media, one of the backers of the hit historical drama “Lincoln”, will launch a cable TV network next summer with programming that focuses on social issues of interest to the millenials generation of teens and young adults.


The channel’s original programming, films and documentaries will be aimed at viewers age 18 to 34 in the large demographic group known as millenials, Participant Media CEO Jim Berk said in an interview on Monday.






Millenials are particularly interested in the type of content that Participant produces about social issues, Berk said. The studio’s credits include the current release “Lincoln”, about President Abraham Lincoln‘s push to ban slavery, last year’s civil rights drama “The Help” and Al Gore climate change documentary “An Inconvenient Truth”.


Participant Media is creating the new network by purchasing two existing cable channels, The Documentary Channel and Halogen TV. After those networks are combined and rebranded, the new channel will reach an estimated 40 million of the more than 100 million U.S. pay-TV subscribers.


The company, founded by billionaire and former eBay Inc President Jeff Skoll with the aim of producing entertaining content that inspires social change, interacts regularly with more than 2.5 million people through social media, local movie screenings and its Takepart.com website, Berk said.


The challenge for Participant will be to sign up additional pay-TV distributors and win viewership in a crowded media landscape. The company is privately held and is not part of a large media conglomerate.


“We have the funding necessary to take a very long-term view, and to spend what we need to spend in terms of programming,” Berk said.


The mainstay of the network’s lineup will be original programming from a variety of genres, said Evan Shapiro, a Participant executive who will run the new network.


The company is developing programming with established Hollywood names including former MTV President Brian Graden, “Inconvenient Truth” director Davis Guggenheim and documentary filmmaker Morgan Spurlock.


Participant also hopes to work with pay-TV distributors to make the channel’s content available on mobile devices such as smartphones and tablets, to meet the viewing patterns of younger audiences, Shapiro said.


(Reporting By Lisa Richwine; Editing by Edmund Klamann)


TV News Headlines – Yahoo! News





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Bird flu kills 4-year-old boy in Indonesia






JAKARTA, Indonesia (AP) — A 4-year-old Indonesian boy has died from bird flu, bringing the death toll to 160 in the world’s hardest-hit country.


Health Ministry official Rita Kusriastuti said Tuesday that the boy died Dec. 6 in Tangerang city, just west of Jakarta, the capital. He developed symptoms of a cold and fever on Nov. 30 and was treated at a public health center before being hospitalized the same day he died.






Kusriastuti said the boy, from the West Java district of Bogor, was believed to have been infected with the H5N1 virus after having direct contact with dead fowl around his house.


Bird flu has killed at least 360 people worldwide since 2003. It remains hard for people to catch, but experts fear it could mutate into a more deadly form.


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‘Rise’ in planning permissions







Planning permission was granted for 33,881 homes across England in July to September, according to figures from the Home Builders Federation (HBF).






It said this was a 36% rise on the 24,872 approvals in the second quarter, and 17% higher than a year earlier.


However, the HBF said the latest figure was still less than the 60,000 approvals it says are needed each quarter to meet demand.


In April, planning law in England was changed to give councils more powers.


Under the National Planning Policy Framework, local authorities are required to work out future housing needs in their area, and then allocate sufficient land to meet it.


The aim of the government is to remove obstacles to the building of new houses, and to speed up planning decisions.


Stewart Baseley, executive chairman of the HBF, said: “The increase is good news and hopefully a reflection of the positive planning principles of the new system. It is just one quarterly increase and we are still well short of the number needed but we hope it starts a trend that will continue in 2013.


“The new system must provide enough viable land to build the number of homes the country needs. Continuing the current low level of house-building is storing up huge social and economic problems for the years ahead and the shortfall must be addressed.”


The HBF is the representative body of the home building industry in England and Wales.


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Egyptians hand Islamists narrow win in constitution vote






CAIRO (Reuters) – Egyptians voted in favor of a constitution shaped by Islamists but opposed by other groups who fear it will divide the Arab world’s biggest nation, officials in rival camps said on Sunday after the first round of a two-stage referendum.


Next week’s second round is likely to give another “yes” vote as it includes districts seen as more sympathetic towards Islamists, analysts say, meaning the constitution would be approved.






But the narrow win so far gives Islamist President Mohamed Mursi only limited grounds for celebration by showing the wide rifts in a country where he needs to build a consensus for tough economic reforms.


The Muslim Brotherhood‘s party, which propelled Mursi to office in a June election, said 56.5 percent backed the text. Official results are not expected until after the next round.


While an opposition official conceded the “yes” camp appeared to have won the first round, the opposition National Salvation Front said in a statement that voting abuses meant a rerun was needed – although it did not explicitly challenge the Brotherhood‘s vote tally.


Rights groups reported abuses such as polling stations opening late, officials telling people how to vote and bribery. They also criticized widespread religious campaigning which portrayed “no” voters as heretics.


A joint statement by seven human rights groups urged the referendum’s organizers “to avoid these mistakes in the second stage of the referendum and to restage the first phase again”.


Mursi and his backers say the constitution is vital to move Egypt’s democratic transition forward. Opponents say the basic law is too Islamist and tramples on minority rights, including those of Christians who make up 10 percent of the population.


The build-up to Saturday’s vote was marred by deadly protests. Demonstrations erupted when Mursi awarded himself extra powers on November 22 and then fast-tracked the constitution through an assembly dominated by his Islamist allies.


However, the vote passed off calmly with long queues in Cairo and several other places, though unofficial tallies indicated turnout was around a third of the 26 million people eligible to vote this time. The vote was staggered because many judges needed to oversee polling staged a boycott in protest.


The opposition had said the vote should not have been held given the violent protests. Foreign governments are watching closely how the Islamists, long viewed warily in the West, handle themselves in power.


“It’s wrong to have a vote or referendum with the country in the state it is – blood and killings, and no security,” said Emad Sobhy, a voter who lives in Cairo. “Holding a referendum with the country as it is cannot give you a proper result.”


INCREASINGLY DIVIDED


As polls closed, Islamists attacked the offices of the newspaper of the liberal Wafd party, part of the opposition National Salvation Front coalition that pushed for a “no” vote.


“The referendum was 56.5 percent for the ‘yes’ vote,” a senior official in the Brotherhood’s Freedom and Justice Party operations room set up to monitor voting told Reuters.


The Brotherhood and its party had representatives at polling stations across the 10 areas, including Cairo, in this round. The official, who asked not to be identified, said the tally was based on counts from more than 99 percent of polling stations.


“The nation is increasingly divided and the pillars of state are swaying,” opposition politician Mohamed ElBaradei wrote on Twitter. “Poverty and illiteracy are fertile grounds for trading with religion. The level of awareness is rising fast.”


One opposition official also told Reuters the vote appeared to have gone in favor of Islamists who backed the constitution.


The opposition initially said its exit polls indicated the “no” camp would win comfortably, but officials changed tack during the night. One opposition official said in the early hours of Sunday that it would be “very close”.


A narrow loss could still hearten leftists, socialists, Christians and more liberal-minded Muslims who make up the disparate opposition, which has been beaten in two elections since Hosni Mubarak was overthrown last year.


They were drawn together to oppose what they saw as a power grab by Mursi as he pushed through the constitution. The National Salvation Front includes prominent figures such as ElBaradei, former Arab League chief Amr Moussa and firebrand leftist Hamdeen Sabahy.


If the constitution is approved, a parliamentary election will follow early next year.


DEADLY VIOLENCE


Analysts question whether the opposition group will keep together until the parliamentary election. The Islamist-dominated lower house of parliament elected earlier this year was dissolved based on a court order in June.


Violence in Cairo and other cities has plagued the run-up to the referendum. At least eight people were killed when rival camps clashed during demonstrations outside the presidential palace earlier this month.


In order to pass, the constitution must be approved by more than 50 percent of those casting ballots. There are 51 million eligible voters in the nation of 83 million.


Islamists have been counting on their disciplined ranks of supporters and on Egyptians desperate for an end to turmoil that has hammered the economy and sent Egypt’s pound to eight-year lows against the dollar.


The army deployed about 120,000 troops and 6,000 tanks and armored vehicles to protect polling stations and other government buildings. While the military backed Mubarak and his predecessors, it has not intervened in the present crisis.


(Additional reporting Yasmin Saleh and Marwa Awad; Writing by Edmund Blair and Giles Elgood; Editing by Tom Pfeiffer)


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Top 5 Apps for Kids This Week






1. PHLIP


Ages 4-up Overall rating: 4.1 out of 5 stars Why we like it: PHLIP is a spatial relations puzzle where you “flip” or turn your screen left or right, like a steering wheel, to change the orientation of the set of tiles, in order to reassemble the picture. You can use photos you take, or choose one from your photo library. Need to know: The more tiles, the harder the puzzle. You can lock any tile by tapping on it. The physical rotation of the device develops motor and cognitive skills and hand-eye coordination. It can also cause your heavy iPad to slip out of your hands. This is a game that works much better on an iPad Mini. Ease of use: 8/10 Educational: 9/10 Entertaining: 7/10 $ 0.99


Click here to view this gallery.






[More from Mashable: How to Crowdsource Your Job Hunt]


Chris Crowell is a veteran kindergarten teacher and contributing editor to Children’s Technology Review, a web-based archive of articles and reviews on apps, technology toys and video games. Download a free issue of CTR here.


In this week’s Top 5 Kids Apps, your kids can play with a spatial puzzle that lets them reassemble photographs they upload themselves. There’s also a chance to learn and have fun with geography trivia and explore Australia with an illustrated story.


[More from Mashable: 4 Benefits of a Job Search Community]


Our friends at Children’s Technology Review shared with us these 5 top apps from their comprehensive monthly database of kid-tested reviews. The site covers everything from math and counting to reading and phonics.


Check back next week for more Top Kids Apps from Children’s Technology Review


Photo via iStockPhoto, cglade


This story originally published on Mashable here.


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Springsteen, Gaga join Stones; Newtown noted






NEW YORK (AP) — Only at a Rolling Stones concert could appearances by Bruce Springsteen and Lady Gaga seem almost like afterthoughts.


Those superstars and other top acts including the Black Keys and John Mayer jammed with the Stones on Saturday night, winding down a series of concerts celebrating the 50th year of rock’s most enduring band (the occasion was also marked by a pay-per-view special).






The Boss rocked out with the band on out “Tumbling Dice”; Gaga matched Mick Jagger shimmy-for-shimmy on “Gimme Shelter”; the Black Keys joined on “Who Do You Love,” and John Mayer and Gary Clark Jr. showed their considerable guitar chops alongside Keith Richards and Ronnie Wood on “Goin’ Down.”


But the Stones would not be upstaged. While the sold-out crowd roared with each special guest, it was the aging but dynamic foursome that generated the most excitement of the night, as they put new energy into their decades-old catalog of hits, including “It’s Only Rock ‘N Roll (But I Like It),” ”Start Me Up,” ”Brown Sugar,” ”Sympathy for the Devil” and more.


The band took a moment to acknowledge the shooting deaths of 20 children and six adults at an elementary school Friday in Newtown, Conn. “We just wanted to send our love and condolences to all the people who lost loved ones in the tragedy in Connecticut,” Jagger early on in the concert as the audience applauded. Jagger noted the entire world was feeling the pain of the stunned nation.


But it was the only somber moment in an a frenetic show that showed why the Stones are considered by many to be the greatest rock band, and belied the much-discussed advanced age of the group’s lineup (their ages range between 65 and 71).


Jagger himself poked fun at the senior citizen status of the band and their fans; speaking of the pay-per-view crowd at home, he joked: “Some of you have got your grandchildren watching you.”


But few acts in their so-called prime would have been able to match the energy the Stones radiated onstage. The group had the crowd on its feet for the entire show as Jagger gyrated across the stage, his voice in top form. Both Wood and Richards dazzled on guitar (Richards got a raucous, sustained ovation as he took over vocals on two songs). And Charlie Watts kept the beat strong on the drums.


Before performing in London together late last month for the first of the concerts, the Stones hadn’t performed in concert together since 2007. Going into these shows, there was some speculation that Saturday’s concert, held at the Prudential Center, might be their last.


Earlier in the evening, Jagger teased that the concert might signal the end: “This could be the last time; I don’t know,” he said. But by the end of the evening, it seemed clear that the question was not when the Stones would return, but when.


“This is the last show of our anniversary tour, and we hope to see you all again soon,” Jagger said.


Perhaps the night’s most special guest was Mick Taylor, the former Stones guitarist who was part of some of their biggest moments from 1969 to 1975, when he left the group. He rejoined his band mates (and the man who replaced him, Wood) onstage for a powerful performance of “Midnight Rambler”.


At the concert’s end, while other special guests gave their final bows and left the stage, Jagger motioned for Taylor to stay, and the five took their final bow together.


___


Nekesa Mumbi Moody is the AP’s Global Entertainment & Lifestyles Editor. Follow her at http://twitter.com/nekesamumbi


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